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KMID : 0359720230410040314
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Journal of the Korean Neurological Association
2023 Volume.41 No. 4 p.314 ~ p.317
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Two Cases of Perinuclear Anti-neutrophil Cytoplastic Antibodies Associated Hypertrophic Pachymeningitis Presented with Visual Loss
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Lee Won-Hyeong
Park Hyo-Jin
Choi Jeong-Yoon
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Abstract
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Pachymeningitis is an inflammatory process mainly involving the dura mater and is possibly associated with infectious, neoplastic, or autoimmune disease. However, in most cases, the etiology remains unknown. Clinical manifestations of pachymeningitis can vary, ranging from headache, cranial neuropathy, cerebellar dysfunction, to seizure. Here we report two cases of perinuclear anti-neutrophil cytoplasmic antibodies associated with pachymeningitis, in both the visual loss attributed to optic neuropathy was the primary sign.
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KEYWORD
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Antibodies, antineutrophil cytoplasmic, Meningitis, Optic nerve diseases
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